The story of The Super Mario Bros. on their journey through the Mushroom Kingdom.

In the year 2065, the next great assault against an invading race of phantom-like aliens is about to be launched. Dr. Aki Ross, a brilliant young scientist, races to find the invaders' secrets, not only to save the planet, but herself as well after her body is infected by alien particles. She teams up with the prestigious Deep Eyes military squadron, led by her old friend Grey Edwards. But as Aki, her mentor Dr. Sid, and Grey work toward a peaceful end, the scheming General Hein devises a plot...